Side effects are usually mild and may include drying and irritation in some users. To test for an adverse reaction to your Proactiv system, apply the products to a small patch of affected skin during the first three days. A small group of people may be hypersensitive or allergic to active ingredients such as benzoyl peroxide, salicylic acid or adapalene, which are in some of the Proactiv products. If you are one of those people, you should not use a product without first discussing use with your healthcare provider. For a full list of product ingredients, please refer to the product packaging.
For side effects specific to Adapalene Gel, please see retinization for further details.
Stop use and ask a doctor if irritation becomes severe, or you have symptoms of an allergic reaction (such as itching, rash, hives, swelling of the lips, eyelids, and shortness of breath).